An illness described as Central Sensitivity Syndrome (CSS) involves something called “central sensitization”.
Pain itself often modifies the way the central nervous system works, so that a patient actually becomes more sensitive and gets more pain with less provocation. It’s called “central sensitization” because it involves changes in the central nervous system (CNS) in particular — the brain and the spinal cord. Sensitized patients are not only more sensitive to things that should hurt, but sometimes to ordinary touch and pressure as well. Their pain also “echoes,” fading more slowly than in other people. There is a “peripheral sensitization” too.
Following an injury or cell damage two main things can occur. Primary hyperalgesia and secondary hyperalgesia. Secondary hyperalgesia is indicative of central sensitization.
Peripheral sensitization is an increased sensitivity to an afferent nerve stimuli. This occurs after there has been an injury or cell damage to the area, and produces a flare response due to nociceptors producing lots of neuropeptides. This then results in an increased sensitivity to heat and touch stimuli which is referred to as primary hyperalgesia or primary allodynia if the stimulus was not a painful one prior to the injury. For example a gentle stroke to the skin which before the injury is not painful but after is interpreted as pain.
The difference between central and peripheral sensitization can be identified quite easily, as peripheral sensitization become heat sensitive whereas central sensitization does not.
Carmen Care Advanced Laser Therapy has created a comprehensive protocol for patients with CSS which includes Laser Energy Detoxification, PSYCH-K and photobiomodulation that provides a significant clinical improvement.